December 4, 2020

parkinsons

Restless leg syndrome, also known as Willis-Ekbom Disease, is a nervous system condition that produces an uncontrollable and severe urge to move your legs. It tends to be a rather unpleasant sensation and is only relieved by moving one's legs, however, this relief is usually temporary. It tends to affect people more at night and can result in sleeplessness due to discomfort. Typically, the conditions tend to worsen with age. There are, however, many things that can be done to manage this condition effectively....
Patients with Parkinson's disease experience a severe lack of dopamine - a neurotransmitter. This is due to the reduction in endogenous production of dopamine in the substantia nigra - the part of the brain that contains an abundance of dopaminergic (dopamine-producing) neurons. With this said, L-dopa (the precursor to dopamine) becomes the foundation of treatment which is why drugs like Sinemet (which contains L-dopa) and Pramipexole (which activates dopamine receptors) are prescribed....